HIPEC & PIPAC
Peritoneal metastasis (cancer spread to the abdominal lining) occurs in a significant number of patients with advanced colorectal, ovarian, gastric, and appendicular cancers. Traditionally, these cases were considered difficult to treat, with limited survival using systemic chemotherapy alone. Studies show that selected patients undergoing Cytoreductive Surgery (CRS) with HIPEC can achieve 5-year survival rates of 30–50% in colorectal and ovarian peritoneal metastasis, which is significantly higher compared to conventional treatment alone.
Organs and Areas Involved
Peritoneum | Abdominal organs
Types of Cancers Covered
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Peritoneal surface malignancies
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Advanced abdominal cancers
How HIPEC & PIPAC Work
HIPEC (Hyperthermic Intraperitoneal Chemotherapy) delivers heated chemotherapy directly into the abdomen immediately after tumor removal surgery, targeting microscopic cancer cells.
PIPAC (Pressurized Intraperitoneal Aerosol Chemotherapy) is a minimally invasive procedure that delivers chemotherapy as a pressurized aerosol, improving drug penetration and offering a treatment option even for patients who may not be suitable for extensive surgery.
These advanced therapies are changing outcomes in carefully selected patients with peritoneal cancers, offering improved survival and better disease control.
Warning Signs to Watch For
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Abdominal swelling
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Persistent abdominal pain
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Loss of appetite
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Digestive discomfort
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Unexplained weight loss
Why Awareness and Early Evaluation Matter
Peritoneal cancers often progress silently and may not cause clear symptoms in the early stages. Many patients present only after developing abdominal swelling, persistent pain, unexplained weight loss, or fluid accumulation in the abdomen. Early evaluation is crucial because timely diagnosis allows better planning of advanced treatments like HIPEC and PIPAC, improves eligibility for curative procedures, and enhances overall survival outcomes. Prompt consultation with a specialist ensures that patients receive the right treatment at the right time, maximizing the chances of disease control and improved quality of life.